Isobutyl Chloroformate

Also known as 2-Methylpropyl chloroformate, 2-Methylpropyl carbonochloridate, Isobutyl chlorocarbonate

CAS number
543-27-1
Molecular formula
C5H9ClO2
Molecular weight
136.58 g/mol
Catalogue number
OS-17316
Purity
≥ 98 %
Grade
Reagent / Synthesis
Packing
25 L

₹1,000 per kg

Specifications

Identity
CAS number 543-27-1
Molecular formula C5H9ClO2
Molecular weight 136.58 g/mol
IUPAC name 2-methylpropyl carbonochloridate
InChIKey YOETUEMZNOLGDB-UHFFFAOYSA-N
SMILES CC(C)COC(=O)Cl
MDL number MFCD00000642
PubChem CID 62365
Physical properties
Appearance Colorless Liquid
Quality
Purity ≥ 98 %
Grade Reagent / Synthesis
Water content ≤ 0.1 %
Stabilizer Without Stabilizer
Packaging
Packaging size 25 L
Packaging type HDPE Bottle

Description and applications

Isobutyl chloroformate (IBCF) is a colorless to light-colored, pungent-smelling liquid primarily used in organic synthesis as an amine-protecting reagent and an activating group for carboxylic acids. It is widely used to form mixed anhydrides in peptide coupling reactions and to block hydroxyl groups during oligonucleotide synthesis.

Applications

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